CD11c
Use
CD11c detection via immunohistochemistry (IHC) helps identify various normal and neoplastic hematopoietic and dendritic cells. In normal tissue, CD11c is expressed on activated CD4/CD8+ T cells, granulocytes, lymphocytes, macrophages, and NK cells. In disease states, CD11c is notably found in acute myeloid leukemia subtypes M4 and M5, hairy cell leukemia, lymphoplasmacytic lymphoma (~81%), small lymphocytic lymphoma (SLL), splenic lymphoma, Langerhans cell histiocytosis, sinus histiocytosis, psoriatic skin lesions, and certain follicular lymphomas.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred specimen type or one unbaked, unstained H&E slide (required) plus two to three positively charged unstained slides (4‑5 microns) per test ordered. Block and slide identifiers should match specimen ID on requisition.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.