CD14
Use
CD14 immunohistochemistry (IHC) identifies expression of the CD14 antigen in cells of monocytic lineages such as macrophages and monocytes, and weakly in granulocytes, Langerhans cells, dendritic cells, and B‑cells. Positive staining is informative in the evaluation of hematologic malignancies including B‑cell chronic lymphocytic leukemia (B‑CLL), follicular center cell lymphoma, diffuse large B‑cell lymphoma (DLBCL), and acute myeloid leukemia subtypes M4/M5.
Special Instructions
This is a technical‑only IHC test. Preferred specimen is a formalin‑fixed, paraffin‑embedded (FFPE) tissue block, or one unbaked, unstained H&E slide (required) plus two to three positively charged unstained slides, all cut at 4‑5 microns per antibody ordered. Specimen labels must match requisition. For transport, use a cold pack not in direct contact with the specimen. New York State clients must provide collection date and time.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
FFPE tissue block preferred, or one unbaked unstained H&E slide (required) plus two to three positively charged unstained slides, cut at 4‑5 microns.