CD31
Use
CD31 is a 130 kDa transmembrane glycoprotein shared by vascular lining cells, megakaryocytes, and platelets. It is highly restricted to endothelial neoplasms among soft tissue tumors, with excellent sensitivity—100 % of angiosarcomas and hemangiomas are CD31 positive. However, Kaposi’s sarcoma is more consistently labeled by CD34 than CD31. CD31 is also used as a prognostic marker for tumor angiogenesis and can stain histiocytes.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
CD31
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred; alternatively, one unbaked, unstained H&E slide (required) plus two to three positively charged unstained slides (4‑5 microns) per test.
Storage Instructions
Use cold pack for transport; cold pack should not be in direct contact with specimen. NYS clients please provide date and time of collection.