CD35
Use
CD35 antigen is a transmembrane protein (160‑250 kDa) binding complement components C3b and C4b and mediates phagocytosis by neutrophils and monocytes. It is expressed in erythrocytes, B‑cells, subset of T‑cells, monocytes, cultured macrophages, neutrophils, eosinophils, glomerular podocytes, and follicular dendritic cells. CD35 IHC is useful in diagnosing mucosa‑associated lymphoid tissue (MALT) lymphoma and studying inflammatory disorders; it also labels follicular dendritic cell sarcoma.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
CD35
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred or one unbaked, unstained H&E‑stained slide (required) plus two to three positively charged unstained slides (4‑5 microns) for each test/antibody ordered. Block and slide identifiers should match specimen ID and labeling on the requisition.
Storage Instructions
Use cold pack for transport, ensuring it's not in direct contact with specimen. NYS clients: provide date and time of collection.