CD44
Use
The CD44 family of glycoproteins exists in a number of variant isoforms, including hematopoietic variant (CD44s) and epithelial cell variant (CD44v). Although many human tumors express CD44, a positive correlation between increased CD44 expression and tumor progression has only been demonstrated in some cases. The most practical application of CD44 immunostaining currently is to distinguish urothelial transitional cell carcinoma in situ from non‑neoplastic changes in the urothelium.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
CD44
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
FFPE tissue block preferred; or one unbaked, unstained slide for H&E staining (required) plus two to three positively charged unstained slides (cut at 4‑5 microns)
Storage Instructions
Use cold pack for transport; cold pack must not contact specimen directly. NYS clients: provide date and time of collection.