CK19
Also known as: Cytokeratin 19
Use
Cytokeratin 19 (CK19) is a member of the type I acidic keratins subfamily and is expressed in various human tissues. It labels ductal and glandular epithelia, prostatic epithelia, and non-keratinizing squamous epithelia. This antibody is useful in diagnosing breast and cervical carcinoma. CK19 is not expressed in hepatocytes, helping to distinguish liver metastasis from hepatocellular carcinomas.
Special Instructions
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred. Ensure block and slide identifiers match exactly with the specimen ID on the requisition.
Limitations
As CK19 is not expressed in hepatocytes, it may be useful in distinguishing between liver metastasis and hepatocellular carcinoma, but may not be reliable for other types of carcinoma or tissues where CK19 is expressed.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Use cold pack for transport, ensuring it does not touch the specimen directly.
Patient Preparation
NYS clients please provide date and time of collection.