FOLR1 FDA (ELAHERE™) for Ovarian Carcinoma

Casandra

Casandra Test Code NG98880Version 1 (DRAFT)

Performing Lab

Lab NeoGenomicsLab Test ID N/A

FOLR1 FDA (ELAHERE™) for Ovarian Carcinoma

Also known as: FOLR1 IHC CDx, Folate Receptor alpha (FR?), FOLR1 (FOLR1-2.1) RxDx Assay, FR-ASSIST™ VENTANA FOLR1 (FOLR1-2.1)

Clinical Use

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Use

The FR? protein is expressed in 90% of ovarian cancers and has limited expression in normal tissue, making it an attractive therapeutic target. In using the VENTANA FOLR1 (FOLR1-2.1) RxDx Assay for the evaluation of ovarian cancer patients, approximately 35% of patients are considered to have high expression of FR?—as defined by the scoring criteria mentioned above— and thus eligible for treatment with ELAHERE™.