HPV RNA ISH
Also known as: HPV RNA ISH 16/18, HPV RNA ISH High Risk Cocktail, HPV RNA ISH Low Risk Cocktail
Use
In situ hybridization on FFPE tissues for qualitative detection of E6/E7 mRNA in up to 28 HPV subtypes—comprising 10 low‑risk and 18 high‑risk types—provides diagnostic information regarding active HPV infection. The complete panel is recommended though partial panels (16/18 High Risk, High Risk Cocktail, Low Risk Cocktail) are accepted. Results indicate which component or cocktail is positive, though they do not identify specific subtypes, aiding in pathogen detection.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Chromosomal / Cytogenetics (ISH)
Biomarkers
HPV
Microorganism
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Block is preferred over cut slides. Send 9‑11 cut slides (minimum 9) plus one H&E slide. Sections must be wrinkle‑ and artifact‑free; no additives in water bath. Cut sections at 4‑5 microns and place tissue at center bottom of positively‑charged slide. Paraffin block should be sent with a cold pack; identifiers must match requisition. Not acceptable: ThinPrep or SurePath Pap vials.
Storage Instructions
Use cold pack for transport (not in direct contact with specimen). NYS clients: provide date and time of collection.