INSM1
Also known as: Insulinoma-associated protein 1
Use
INSM1 is a transcription factor that is a sensitive and specific marker for neuroendocrine tumors. It is a nuclear stain and performs as well, if not better, than synaptophysin and is superior to chromogranin. It is rarely expressed in adenocarcinoma or squamous cell carcinomas without neuroendocrine differentiation.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
INSM1
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.