JAK2 V617F Mutation Analysis - Quantitative

Casandra

Casandra Test Code NG49325Version 1 (DRAFT)

Performing Lab

Lab NeoGenomicsLab Test ID N/ACPT Code 81270

JAK2 V617F Mutation Analysis - Quantitative

Also known as: JAK2 V617F Quantitative Analysis

Clinical Use

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Use

The JAK2 V617F mutation is present in approximately 90% of polycythemia vera (PV) cases and approximately half of primary myelofibrosis (PMF) or essential thrombocythemia (ET). Quantitation of V617F is useful for monitoring myeloproliferative neoplasm (MPN) patients’ response to clinical treatment because mutational load correlates with disease course, making it a useful predictive marker.

Special Instructions

Test is DNA‑based. Extract & Hold – DNA service should be selected if specimen hold is desired. Sodium Heparin tubes are acceptable. Use a cold pack for transport (not in direct contact with specimen), ship same day when possible. New York State (NYS) clients must provide date and time of collection.