KRAS Mutation Analysis by PCR
Use
The KRAS Mutation Analysis Assay is a real-time PCR-based assay designed to detect somatic mutations in exons 2, 3 and 4 of the KRAS gene, including Exon 2 mutations G12C, G12A/D/R/V/S and G13D; Exon 3 mutations A59E/G/T and Q61H/L/R; and Exon 4 mutations K117N/R/E and A146T/P/V. This information supports clinical decision-making in cancers where KRAS mutation status informs targeted therapy choices.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
PCR-based (RT-PCR)
Biomarkers
Result Turnaround Time
7 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Paraffin block preferred; alternatively send 1 H&E slide plus 5‑10 unstained slides cut at 5 μm or more, on positively‑charged slides, fixed in 10% neutral buffered formalin; do not use zinc fixatives.
Storage Instructions
Use cold pack for transport, ensuring the cold pack is not in direct contact with the specimen. NYS clients please provide date and time of collection.