Use

Each test contains a set of oligonucleotide probes targeting lambda light chain immunoglobulin mRNA in the cytoplasm of immunoblastic cells, plasma cells, and plasmacytoid cells. Assessing light chain mRNA restriction helps distinguish between neoplastic and reactive lymphoid proliferations and aids in evaluating multiple myeloma, plasmacytoma, lymphomas with plasmacytoid or immunoblastic features, and reactive plasma cell proliferations.