LMO2
Use
LMO2 protein is expressed in normal human germinal‑center (GC) and GC‑derived lymphomas and at high levels in endothelial cells, spleen, hematopoietic precursors, and a significant proportion of acute lymphoblastic and myeloid leukemias. In diffuse large B‑cell lymphoma (DLBCL), LMO2 expression aligns with germinal‑center markers HGAL, CD10 and BCL6, indicating a potential role in prognostic stratification of DLBCL patients. It is rarely expressed in mature T, natural killer (NK), and plasma cell neoplasms and is absent from non‑hematolymphoid tissues, except endothelial cells.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2‑3) positively charged unstained slides (all cut at 4‑5 microns) for each test/antibody ordered. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.