Casandra
Casandra Test Code NG06946Version 1 (DRAFT)
Performing Lab
MET Exon 14 Deletion Analysis
Also known as: MET Exon 14 Skipping
Clinical Use
Order TestUse
This assay detects alternative splice junctions leading to exon 14 skipping (deletion) in the MET gene, which can be an important actionable molecular alteration in certain cancers, particularly lung tumors. It is available both as a standalone test and as part of the NeoTYPE® Lung Tumor Profile.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
PCR-based (RT-PCR)
Biomarkers
MET Exon 14 Deletion
SignatureSplice Variant
Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
14 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
FFPE solid tumor tissue: paraffin block preferred; alternatively, 1 H&E slide plus 5–10 unstained slides cut at ≥5 microns, positively‑charged slides, 10% NBF fixative; do not use zinc fixatives.