MYC Amplification for Angiosarcoma
Also known as: c-MYC Amplification
Use
Fluorescence in situ hybridization (FISH) testing for MYC gene amplification (8q24) assists in the diagnostic evaluation of angiosarcoma by detecting increased MYC copy number relative to centromere 8, providing evidence of amplification status.
Special Instructions
Level of Service options include Global and Tech Only. For tech‑only orders, a circled H&E slide is required along with the paraffin block and unstained slides. Specimen must be transported with a cold pack, not in direct contact with the specimen.
Limitations
Not provided.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Send paraffin block. Also send circled H&E slide for tech‑only (required). Cut slides: H&E slide (required) plus 4 unstained slides cut at 4‑5 microns. Circle H&E slide for tech‑only.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.