NeoTYPE® Head & Neck Tumor Profile

Casandra

Casandra Test Code NG27982Version 1 (DRAFT)

Performing Lab

Lab NeoGenomicsLab Test ID N/ACPT Codes 81457, 88342, 88360, 88365, 88377

NeoTYPE® Head & Neck Tumor Profile

Also known as: Head & Neck Tumor Profile

Clinical Use

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Use

The NeoTYPE Head & Neck Tumor Profile provides comprehensive analysis of 34 biomarkers through a combination of next-generation sequencing (NGS), FISH, IHC, and other molecular methods. This test is designed to guide treatment decisions by offering insight into the genetic landscape of head and neck tumors. NGS includes 27 genes and two biomarkers, allowing detailed genetic profiling and identification of mutations and genomic alterations in tumors. The inclusion of multiple methodologies ensures a thorough evaluation, facilitating tailored treatment approaches based on the individual tumor profile.

Special Instructions

Test orders include a summary interpretation of all results. If Pan-TRK IHC is expressed or equivocal, reflex to either NTRK NGS Fusion Panel or NTRK 1-3 FISH Panel will be added. An indeterminate MSI result by NGS will reflex to MSI by PCR if tumor percentage is ≥40% and paired normal tissue is available. Please ensure proper storage and transportation using a cold pack, ensuring it is not in direct contact with the specimen. NYS clients should provide the date and time of collection.

Limitations

The test may not detect all possible genetic mutations and may have limitations if the tumor sample is insufficient or degraded. Reflex testing is contingent on specific initial results and may delay final reporting. The interpretative accuracy of the analyses depends on sample quality, including fixation method and preservation. Extensive genetic rearrangements or rare mutations beyond the targeted regions may not be identified, and further genetic consultation may be necessary.

Test Details

New York Approved