NeoTYPE Liver/Biliary Tumor Profile
Also known as: Liver/Biliary Tumor Profile
Use
The NeoTYPE Liver/Biliary Tumor Profile aids in the diagnosis and treatment guidance of liver and biliary tumors through a comprehensive analysis of genetic mutations and expressions. It evaluates 38 biomarkers using NGS, FISH, and IHC methodologies, providing summary interpretations of results to guide treatment decisions. Reflex testing for indeterminate microsatellite instability (MSI) and Pan-TRK IHC findings enhances diagnostic accuracy and therapeutic targeting.
Special Instructions
Ensure FFPE tissue is fixed in 10% buffered formalin, avoiding zinc fixatives. Cold pack transportation is required, ensuring no direct contact with the specimen. Specific CPT codes apply based on reflex testing performed, which should align with AMA guidelines.
Limitations
The test is limited to the analysis of select biomarkers relevant to liver and biliary tumors and may not detect all possible genetic alterations. Reflex tests such as MSI by PCR depend on tumor percentage and availability of paired normal tissue. Analytical sensitivity and specificity may vary by biomarker and are subject to complex interpretation.
New York Approved
Methodology
NGS (Targeted)
Biomarkers
Result Turnaround Time
14 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Paraffin block preferred
Storage Instructions
Use cold pack for transport, ensuring it is not in direct contact with specimen.