Use

The NTRK & RET NGS Fusion Profile is an RNA-based next-generation sequencing panel that detects translocations and fusions of the genes NTRK1, NTRK2, NTRK3, and RET, including known and novel fusion partners. It also detects point mutations in select exons of these genes. This test may be utilized to select patients for FDA-approved therapies, such as ROZLYTREK® (entrectinib) and VITRAKVI® (larotrectinib) for NTRK, and GAVRETO (pralsetinib) and RETEVMO (selpercatinib) for RET.