p16
Use
p16 (INK4a, p16‑MTS1), the product of the CDKN2 gene, is a tumor suppressor that inhibits progression through the G1 cell cycle phase. Its expression is frequently altered in tumors (e.g., melanomas, gliomas, esophageal, pancreatic, lung, urinary bladder carcinomas, leukemias) and is associated with high‑risk human papillomavirus in cervical and head and neck cancers.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded tissue block preferred. Or one unbaked, unstained slide for H&E staining (required) plus two to three positively charged unstained slides (cut at 4‑5 microns) per test/antibody ordered. Block and slide identifiers must match requisition.
Storage Instructions
Use cold pack for transport; cold pack must not touch specimen directly. NYS clients: provide date and time of collection.