p40
Use
The p40 antibody targets ΔNp63, an isoform of p63, offering equivalent sensitivity to p63 for detecting squamous cell carcinoma with markedly superior specificity—reducing misinterpretation of p63‑positive adenocarcinomas as squamous cell carcinoma. This supports routine use of p40 in diagnosing pulmonary squamous cell carcinoma.
Special Instructions
Tech Only level of service. Use of a formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred; alternatively, one unbaked, unstained H&E slide plus two to three positively charged unstained slides (4‑5 µm) are required. Block and slide identifiers must match specimen ID on the requisition. Transport using a cold pack not in direct contact with specimen; New York State clients must include date and time of collection.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred; or one unbaked unstained H&E slide (required) plus two to three positively charged unstained slides at 4‑5 µm, matching specimen ID on requisition.
Storage Instructions
Use cold pack for transport, not in direct contact with specimen; NYS clients provide date and time of collection.