P504S
Use
Expression of P504S protein, or Alpha‑methylacyl‑CoA Racemase (AMACR), is found in prostatic adenocarcinoma but not in benign prostatic tissue. It also stains premalignant lesions of the prostate, high‑grade prostatic intraepithelial neoplasia (PIN), and atypical adenomatous hyperplasia. P504S stains the vast majority of prostate cancers and has been shown to stain numerous other tumor types, such as hepatoma, breast carcinoma, pancreatic islet tumor, and desmoplastic small round cell tumor.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
P504S
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred specimen type or one unbaked, unstained slide for H&E staining (required) and two to three (2‑3) positively charged unstained slides (all cut at 4‑5 microns) for each test/antibody ordered. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.