Casandra
Casandra Test Code NG22841Version 1 (DRAFT)
Performing Lab
PDGFB Rearrangement (22q13)
Also known as: Platelet-derived growth factor beta
Clinical Use
Order TestUse
Detection of PDGFB gene rearrangements (at locus 22q13.1) using fluorescence in situ hybridization (FISH) for diagnosis of dermatofibrosarcoma protuberans (DFSP).
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
PDGFB
GeneStructural Rearrangement(s) • Fusion • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Paraffin block or slides
Collection Instructions
Send paraffin block. Also send circled H&E slide for tech‑only. For cut slides: H&E slide plus 4 unstained slides cut at 4‑5 microns. Circle H&E slide for tech‑only.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.