Casandra
Casandra Test Code NG75369Version 1 (DRAFT)
Performing Lab
PRAME
Clinical Use
Order TestUse
PRAME (PReferentially expressed Antigen in MElanoma) is expressed in about 90% of melanoma subtypes and is negative in about 85% of cutaneous melanocytic nevi. Immunohistochemical analysis of PRAME may be useful for diagnostic purposes to support the diagnosis of melanoma.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
PRAME
ProteinExpression
Expression • Ordinal Score (e.g., TPS, CPS, H-score)
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin-fixed, paraffin-embedded (FFPE) tissue block preferred; or one unbaked, unstained H&E slide (required) plus two to three positively charged unstained slides (4–5 µm) for each test/antibody ordered. Block and slide identifiers must match requisition.
Storage Instructions
Use cold pack for transport; cold pack not in direct contact with specimen.