PSMA
Also known as: Prostate Specific Membrane Antigen
Use
Prostate specific membrane antigen (PSMA) is a 750 amino acid type II membrane glycoprotein with folate hydrolase and neuropeptidase activity. PSMA is expressed in normal and malignant prostatic epithelium and in a subset of non‑prostatic tissues. In prostate cancer, PSMA expression has been shown to correlate with disease progression, with the highest levels expressed in hormone‑refractory and metastatic disease. PSMA expression has also been reported on the neovasculature of a variety of non‑prostatic solid tumors.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
PSMA
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
FFPE tissue block preferred or one unbaked, unstained slide for H&E (required) plus two to three positively charged unstained slides (4‑5 microns), identifiers must match requisition.
Storage Instructions
Use cold pack for transport; cold pack not in direct contact with specimen. NYS clients: provide date and time of Collection.