TERT Promoter Mutation Analysis
Also known as: TERT Promoter Mutation
Use
This test is used to identify mutations in the promoter region of the TERT gene, which can be significant in understanding tumor characteristics and possible prognostic implications.
Special Instructions
Use positively-charged slides and 10% NBF fixative. Avoid zinc fixatives. Utilize cold packs for specimen transport without direct contact.
Limitations
The analysis is limited to the detection of mutations in the promoter region of the TERT gene using Sanger sequencing and may not detect all types of genetic variants.
Methodology
Sanger
Biomarkers
Result Turnaround Time
14 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Paraffin block or slides
Collection Instructions
Use 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns.
Storage Instructions
Use cold pack for transport, ensuring indirect contact.
Causes for Rejection
Use of zinc fixatives.