Thrombomodulin (TM)
Use
Thrombomodulin (TM) is a plasma membrane‑related glycoprotein with anticoagulant activity, present in various cell types including megakaryocytes, mesangial cells, synovial cells, mesothelial cells, endothelial cells, and some squamous epithelial cells and associated tumors. TM antibody often shows thick membranous staining in most mesotheliomas and cytoplasmic immunostaining in approximately half of pulmonary adenocarcinomas. It is also a marker of urinary bladder epithelium.
Special Instructions
Level of Service: Tech Only. NYS clients: provide date and time of collection. Use cold pack for transport, ensuring cold pack is not in direct contact with specimen.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred specimen type or one unbaked, unstained slide for H&E staining (required) and two to three (2‑3) positively charged unstained slides (all cut at 4‑5 microns) for each test/antibody ordered.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.