TIA1
Use
TIA1 is a 15 kDa cytoplasmic granule-associated protein expressed in lymphocytes with cytolytic potential. Immunohistochemistry using a monoclonal antibody to TIA1 is useful in the identification of cytotoxic T‑cell and NK‑cell neoplasms; most anaplastic large cell lymphomas and various T‑ and NK‑cell lymphomas/leukemias are positive, while B‑cell lymphomas, Hodgkin lymphomas, and lymphoblastic leukemias are negative.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
TIA1
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred specimen type or one unbaked, unstained slide for H&E staining (required) plus two to three positively charged unstained slides (cut at 4‑5 microns) for each test/antibody ordered. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.