Amelogenesis and Dentinogenesis Imperfecta Panel
Use
This test is intended for individuals with clinical or suspected diagnoses of amelogenesis imperfecta or dentinogenesis imperfecta. These conditions are characterized by defects in tooth enamel and dentin formation, leading to issues such as discoloration, increased risk of cavities, and tooth wear. Genetic testing can confirm the diagnosis, guide treatment decisions, and inform family planning by identifying variants responsible for these conditions.
Special Instructions
PreventionGenetics offers this panel, and testing must be ordered by a licensed healthcare provider. Ensure the inclusion of detailed clinical information and family history, as these are crucial for accurate interpretation.
Limitations
While the panel is comprehensive, covering 34 genes associated with enamel and dentin defects, negative results do not rule out the possibility of variants in genes not included in the panel or in non-coding regions of the genome. Variants of uncertain significance may also be identified.
New York Approved
Methodology
NGS (Targeted)
Biomarkers
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
Not provided