Use

The Hereditary Paraganglioma and Pheochromocytoma Panel is designed for individuals with clinical or suspected diagnoses of hereditary paraganglioma or pheochromocytoma. This includes individuals with multiple, multifocal, bilateral, early-onset (<45 years) or familial paragangliomas/pheochromocytomas, as well as those with extra-adrenal or metastatic paragangliomas/pheochromocytomas. It also targets individuals with SDHB-deficient paragangliomas/pheochromocytomas by immunohistochemistry and those with personal or family histories consistent with syndromic presentations (e.g., MEN1, MEN2, NF1, VHL, HLRCC).