Parkinson Disease via the LRRK2 Gene
Use
This test is designed for individuals with relevant features who have a clinical or suspected diagnosis of LRRK2-related Parkinson disease. It is also required for individuals of Ashkenazi Jewish or North African Berber ancestry suffering from Parkinson's disease. The test focuses on the LRRK2 gene, known to be associated with an increased risk of Parkinson's disease.
Special Instructions
Turnaround time is 2 - 3 weeks (7 - 16 days if STAT option is selected). Specimens from individuals may consist of blood, DNA, buccal swap, saliva, or tissue, especially if they are collected through the Exome Platform. Genome Platform requires blood or DNA specimens exclusively.
Limitations
The test is not intended for detection of all potential genetic variations related to Parkinson's disease. Only alterations or copy number variations (CNVs) in the LRRK2 gene are analyzed. The analyses are limited to what can be detected through NGS and CNV using either the Exome or Genome platform.
Methodology
NGS (Other)
Biomarkers
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
See platform-specific requirements for specimen types.