Aluminum, 24‑Hour Urine without Creatinine
Use
Determines total aluminum excreted in a 24‑hour urine collection, useful for monitoring aluminum exposure in settings such as dialysis patients or those with occupational/environmental exposure; evaluation of prosthetic implant wear; cannot be substituted with serum aluminum measurements. Clinical interpretation should consider renal function and context. (Source: Mayo Clinic Laboratory description)
Special Instructions
Requires collection of total 24‑hour urine volume (in milliliters). Specimens for metal analysis must be collected in acid‑washed or metal‑free containers to avoid contamination. Avoid collection after administration of gadolinium‑ or iodine‑containing contrast media within prior 96 hours. Record total volume on container and requisition. (Sources: Mayo Clinic Labs spec instructions, Medfusion instructions)
Limitations
Falsely elevated results may occur if non‑acid‑washed or metal‑cap containers are used. Preanalytical contamination is a major source of error in trace metals assays. Results should always be interpreted in clinical context. (Source: Mayo Clinic limitations and cautions)
New York Approved
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
2-8 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
10 mL aliquot (well‑mixed 24‑hour urine)
Minimum Volume
3 mL
Container
Plastic acid‑washed or metal‑free container (transport), clean plastic urine container with no metal cap (collection)
Collection Instructions
Collect urine for 24 hours; record total volume on container and requisition; transport an aliquot in acid‑washed/metal‑free container; refrigerate within 4 hours of completion; avoid gadolinium/iodine contrast within previous 96 hours.
Storage Instructions
Refrigerate within 4 hours and transport accordingly
Causes for Rejection
Use of non‑acid‑washed containers or metal caps; contamination risks.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | up to 5 days |
| Refrigerated | up to 14 days |
| Frozen | up to 30 days |