Calcitonin, IHC with Interpretation
Use
Immunohistochemical staining for calcitonin aids in identifying C‑cells of the thyroid, medullary thyroid carcinoma, and other neuroendocrine tumors; interpretation provides diagnostic insight by a pathologist in clinical context.
Special Instructions
Order includes pathologist interpretation with the immunostain; ensure adequate clinical history is provided for accurate interpretation.
Limitations
Performance depends on fixation quality; use of fixatives other than 10% neutral buffered formalin may yield unsatisfactory staining results.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Tumor Tissue (FFPE)
Volume
0.2 cm × 0.2 cm × 0.2 cm tissue; minimum 2 slides per antibody
Minimum Volume
Not provided
Container
Paraffin block or precut unstained slides mounted on positively charged slides
Collection Instructions
Well‑fixed (10% formalin) tissue; send block with corresponding H&E and/or unstained slides; if precut slides, air‑dry, do not oven dry, send within 6 weeks of cutting.
Storage Instructions
Store and transport at room temperature; during summer, use cooled container.
Causes for Rejection
Use of alternative fixatives; oven‑dried or poorly fixed tissue; depleted specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |