Catecholamines, Fractionated, Plasma
Also known as: Catecholamines, Free, Dopamine, Epinephrine, Noradrenalin
Use
Measurement of plasma fractionated catecholamines (epinephrine, norepinephrine, dopamine, total catecholamines) is used to assess neuroendocrine conditions such as pheochromocytoma or paraganglioma, and can assist in evaluation of hypertensive patients or those with orthostatic hypotension.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
2-6 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL preferred (1 mL minimum)
Minimum Volume
1 mL
Container
Green-top (sodium heparin) tube; acceptable: EDTA (lavender-top) tube
Collection Instructions
Draw blood in prechilled sodium heparin tube; centrifuge within 30 minutes; separate plasma; freeze immediately; label as “supine” or “upright” if applicable.
Patient Preparation
Overnight fasting; patient relaxed in supine or upright; avoid alcohol, coffee, tea, tobacco, strenuous exercise prior to collection.
Causes for Rejection
Thawed specimens unacceptable
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 6 hours |
| Refrigerated | 6 hours |
| Frozen | 30 days |