Chlamydia/Neisseria gonorrhoeae RNA, TMA, Rectal

Also known as: CT/GC TMA, CT/NG TMA, CT/NG Aptima, CT/GC Aptima

Clinical Use

Use

This nucleic acid amplification test (NAAT), employing transcription‑mediated amplification (TMA), is used to detect RNA from both Chlamydia trachomatis and Neisseria gonorrhoeae in rectal swab specimens of patients with potential exposure or symptoms in extragenital sites. It facilitates early and accurate diagnosis of anorectal infections in at-risk populations (including men who have sex with men and sexually active individuals engaging in anal intercourse), enhancing targeted treatment and reducing transmission risk.

Special Instructions

Not provided.

Limitations

Positive results are considered presumptive evidence of infection; repeat testing of the same positive sample using the same methodology is generally not recommended. Confirmatory testing using an assay targeting an alternate nucleic acid region may be considered in populations with low disease prevalence or when false‑positive results may have significant consequences.

Test Details

Methodology

Other

Biomarkers

Chlamydia trachomatis

Microorganism

Other

Other • Binary (Detected / Not Detected)

Neisseria gonorrhoeae

Microorganism

Other

Other • Binary (Detected / Not Detected)

Result Turnaround Time

1-2 days

Specimen

Other

Volume

Not provided

Minimum Volume

Not provided

Container

APTIMA Unisex Swab Specimen Collection Kit (or Vaginal Swab Specimen Collection Kit or Multi‑Test Collection Tube)

Collection Instructions

Insert small blue (or pink) shafted swab approximately 3‑5 cm into rectum, rotate ≥3 times against rectal wall, withdraw carefully, place into APTIMA transport tube, break shaft, recap, label and send.