Chlamydia/Neisseria gonorrhoeae RNA, TMA, Rectal
Also known as: CT/GC TMA, CT/NG TMA, CT/NG Aptima, CT/GC Aptima
Use
This nucleic acid amplification test (NAAT), employing transcription‑mediated amplification (TMA), is used to detect RNA from both Chlamydia trachomatis and Neisseria gonorrhoeae in rectal swab specimens of patients with potential exposure or symptoms in extragenital sites. It facilitates early and accurate diagnosis of anorectal infections in at-risk populations (including men who have sex with men and sexually active individuals engaging in anal intercourse), enhancing targeted treatment and reducing transmission risk.
Special Instructions
Not provided.
Limitations
Positive results are considered presumptive evidence of infection; repeat testing of the same positive sample using the same methodology is generally not recommended. Confirmatory testing using an assay targeting an alternate nucleic acid region may be considered in populations with low disease prevalence or when false‑positive results may have significant consequences.
Methodology
Other
Biomarkers
Chlamydia trachomatis
MicroorganismNeisseria gonorrhoeae
Microorganism
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Not provided
Minimum Volume
Not provided
Container
APTIMA Unisex Swab Specimen Collection Kit (or Vaginal Swab Specimen Collection Kit or Multi‑Test Collection Tube)
Collection Instructions
Insert small blue (or pink) shafted swab approximately 3‑5 cm into rectum, rotate ≥3 times against rectal wall, withdraw carefully, place into APTIMA transport tube, break shaft, recap, label and send.
Causes for Rejection
Gross fecal contamination; transport tube with 2 swabs; non‑APTIMA swabs; broken containers; M4 or VCM transport media
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 30 Days |
| Refrigerated | 30 Days |
| Frozen | 30 Days |
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