Casandra
Casandra Test Code QD61599Version 1 (DRAFT)
Performing Lab
CSF3R Mutation Analysis
Also known as: Myeloproliferative neoplasm, CNL, Atypical Chronic Myeloid Leukemia (aCML), aCML, Chronic Neutrophilic Leukemia (CNL)
Clinical Use
Order TestUse
This advanced DNA‑based, next‑generation sequencing (NGS) assay analyzes leukocytes from blood or bone marrow aspirate for mutations in exons 14 and 17 of colony stimulating factor 3 receptor (CSF3R). Mutations in these two regions of CSF3R are associated with myeloid neoplasms, particularly atypical chronic myeloid leukemia (aCML) and chronic neutrophilic leukemia (CNL).
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
NGS (Targeted)
Biomarkers
CSF3R
GeneSNV/Indel • Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
4 mL
Minimum Volume
3 mL
Container
EDTA (lavender‑top) tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | Unacceptable |