Estradiol and Estrone
Use
This test measures ultrasensitive estradiol along with estrone using LC‑MS/MS methodology, intended for accurate quantitation of estrogen levels in serum. It is utilized in evaluating estrogen status across a range of patient populations, accounting for phases such as follicular, luteal, postmenopausal, as well as specific pediatric and adult reference intervals.
Special Instructions
Norethindrone acetate/Norethisterone acetate is known to interfere with estrone measurement using Quest Diagnostics LC‑MS/MS. Not valid in patients taking these drugs. Age and sex must be specified on the test request form.
Limitations
Reject criteria include serum separator tube that is grossly icteric or shows gross hemolysis. Interference may occur with certain exogenous steroid compounds. Ensure proper sample quality and patient information to avoid misinterpretation.
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Container
Serum separator tube
Causes for Rejection
Grossly icteric; gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 7 days |
| Frozen | 28 days |