Estriol, LC/MS/MS, Serum
Use
The placenta converts DHEA‑S produced by the fetal adrenals to estriol and other estrogens. Estriol is useful in assessing fetal adrenal and placental function during pregnancy and is commonly used as one of the maternal serum biochemical markers for screening chromosomal trisomies such as Down syndrome.
Special Instructions
Not provided.
Limitations
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics and has not been cleared or approved by the FDA. It has been validated under CLIA regulations and is used for clinical purposes.
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
0.3 mL
Container
standard transport tube
Collection Instructions
Centrifuge plain red and aliquot 0.5 mL (Min: 0.3 mL) serum into a standard transport tube
Storage Instructions
Refrigerated
Causes for Rejection
Samples received in SST tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 days |
| Refrigerated | 7 days |
| Frozen | 28 days |