Casandra
Casandra Test Code QD04415Version 1 (DRAFT)
Performing Lab
Everolimus, Blood
Clinical Use
Order TestUse
Therapeutic drug monitoring of everolimus (a mammalian target of rapamycin inhibitor) is utilized to optimize dosing to achieve therapeutic efficacy while minimizing toxicity. Whole blood trough levels are typically measured to guide dosage adjustments in transplant recipients, particularly renal and hepatic transplant patients, where maintaining concentrations within a target range is essential for preventing graft rejection and reducing adverse effects.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Mass Spectrometry
Biomarkers
Everolimus
AnalyteEverolimus • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
2 mL
Minimum Volume
1 mL
Container
EDTA (lavender-top) tube
Collection Instructions
Collect specimen 1 hour prior to next dose (12 hour trough)
Causes for Rejection
Clotted
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 days |
| Refrigerated | 7 days |
| Frozen | 30 days |
