Casandra
Casandra Test Code QD07842Version 1 (DRAFT)
Performing Lab
FISH, TCL1, 14q32.1
Clinical Use
Order TestUse
The proto‑oncogene TCL1 located at 14q32.1 is overexpressed in a variety of lymphoid neoplasms, including T‑cell prolymphocytic leukemia (T‑PLL), T‑cell acute lymphoblastic leukemia/lymphoma (T‑ALL/LBL), Epstein‑Barr virus (EBV)‑infected B‑cell lymphomas and AIDS‑related lymphomas. The overexpression of TCL1 usually results from juxtaposition to a T‑cell receptor locus via a translocation or inversion.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Unknown CNV
Copy Number RegionFISH • Copy Number • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Bone Marrow
Volume
3 mL (1 mL minimum) bone marrow
Minimum Volume
1 mL
Container
sodium heparin (green‑top) tube
