Helicobacter pylori, Urea Breath Test
Also known as: H.pylori Urea Breath Test, H.pylori UBIT, H pylori UBIT, H pylori Urea Breath Test, UBT
Use
Helicobacter pylori is a gram-negative microaerophilic curved bacillus with an affinity for human gastric mucosa. H. pylori has been identified as an important pathogen in the upper GI tract. The causal relationship between H. pylori and chronic active gastritis, duodenal ulcers, and gastric ulcers has been well documented. The PyloPlus® UBT breath test provides a non‑invasive and non‑hazardous method for detecting current H. pylori infection using urea breath analysis.
Special Instructions
Use the PyloPlus™ UBT collection kit consisting of paired breath sample bags (baseline and post‑dose), citric acid flavoring, ¹³C‑urea powder, and instructions. Patients must fast at least one hour before the baseline sample. Avoid antimicrobials, proton pump inhibitors, and bismuth preparations within two weeks prior to testing. Use only properly capped collection bags, submit paired samples together, and ensure specimens are submitted with the kit’s zip‑lock bag.
Limitations
Specimens other than those collected in PyloPlus® UBT collection bags are rejected; uncapped or single collection bags, insufficient breath volume, and specimens from patients younger than 3 years old are not acceptable. Antimicrobials, PPIs, or bismuth within two weeks may cause false negatives. Insufficient data for pregnant or lactating women.
Methodology
Other
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Paired breath samples (pre and post)
Minimum Volume
Not provided
Container
PyloPlus® UBT Collection Kit breath bags (blue and pink)
Collection Instructions
Collect baseline (blue) then post‑dose (pink) breath samples using kit instructions; cap immediately; submit paired samples together in kit zip‑lock bag.
Patient Preparation
Fast at least one hour before baseline. Avoid antimicrobials, proton pump inhibitors, and bismuth preparations within two weeks.
Causes for Rejection
Specimens collected in non‑PyloPlus® UBT bags; insufficient breath; single collection bags; uncapped bags; specimens from patients <3 years old
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |