Hepatitis E Virus Antibodies (IgG/IgM)
Use
Hepatitis E virus (HEV) is the major etiologic agent of enterically transmitted non‑A, non‑B hepatitis worldwide and has a high case‑fatality rate in pregnant women. Both IgM and IgG antibody to HEV (anti‑HEV) are produced following infection. The titer of IgM anti‑HEV declines rapidly during early convalescence; IgG anti‑HEV persists and appears to provide at least short‑term protection against disease. Both HEV IgM and IgG are typically detected within one month after infection; IgM persists for about two months, whereas IgG levels persist for months to years after recovery. Approximately 20% of the U.S. population is positive for HEV IgG, indicating that HEV exposure is more common than previously thought.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (ELISA)
Biomarkers
HEV IgG antibody
ProteinHEV IgM antibody
Protein
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
no additive (red‑top) tube transferred to plastic screw‑cap vial
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 30 days |
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