Herpesvirus 7 (HHV‑7) DNA, Quantitative Real‑Time PCR
Also known as: Roseola, HHV7, HHV7 DNA
Use
This test is used in the diagnosis of human herpesvirus 7 (HHV‑7) infection. HHV‑7 is closely related to HHV‑6 and CMV, and can cause reactivation in transplant patients or other immunocompromised individuals. PCR may detect infection earlier than immunologic methods and provides more rapid results than culture, but does not provide information on past exposure or immunity. Quantitative measurement may provide information on disease regression.
Special Instructions
Not provided.
Limitations
This assay was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The test has been validated pursuant to CLIA regulations and is used for clinical purposes. Quantitative PCR does not provide information on past exposure or immunity; it only indicates presence of viral DNA. PCR may be more rapidly positive than culture, but limitations include inability to confirm latency versus active replication.
Methodology
PCR‑based (PCR)
Biomarkers
LOINC Codes
- 49397‑3
- 49397‑3
- 31208‑2
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.3 mL
Container
EDTA (lavender‑top) tube
Collection Instructions
Collect and send 1 mL whole blood in EDTA (lavender‑top) tube; do not freeze; refrigerated transport preferred; ambient acceptable up to 48 hours, refrigerated up to 7 days.
Causes for Rejection
Samples collected in lithium or sodium heparin
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 7 days |
| Frozen | 30 days |