Herpesvirus 7 (HHV‑7) DNA, Quantitative Real‑Time PCR

Also known as: Roseola, HHV7, HHV7 DNA

Clinical Use

Use

This test is used in the diagnosis of human herpesvirus 7 (HHV‑7) infection. HHV‑7 is closely related to HHV‑6 and CMV, and can cause reactivation in transplant patients or other immunocompromised individuals. PCR may detect infection earlier than immunologic methods and provides more rapid results than culture, but does not provide information on past exposure or immunity. Quantitative measurement may provide information on disease regression.

Special Instructions

Not provided.

Limitations

This assay was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The test has been validated pursuant to CLIA regulations and is used for clinical purposes. Quantitative PCR does not provide information on past exposure or immunity; it only indicates presence of viral DNA. PCR may be more rapidly positive than culture, but limitations include inability to confirm latency versus active replication.

Test Details

Methodology

PCR‑based (PCR)

Biomarkers

HHV‑7

Microorganism

DNA Quantitation

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

49397‑3

Result Codes

49397‑3
31208‑2

Result Turnaround Time

1-2 days

Specimen

Whole Blood

Volume

1 mL

Minimum Volume

0.3 mL

Container

EDTA (lavender‑top) tube

Collection Instructions

Collect and send 1 mL whole blood in EDTA (lavender‑top) tube; do not freeze; refrigerated transport preferred; ambient acceptable up to 48 hours, refrigerated up to 7 days.