Histamine, 24‑Hour Urine
Use
Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.
Special Instructions
Patient should avoid direct sunlight during the 24‑hour collection. Patient should refrain from taking antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours prior to specimen collection.
Limitations
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Methodology
Immunoassay (IA)
Biomarkers
LOINC Codes
- 3167‑4
- 9410‑2
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
4 mL
Minimum Volume
2 mL
Container
leak‑proof container (24‑hour urine) with 10 mL 6N HCl preservative
Collection Instructions
Collect 24‑hour urine containing 10 mL 6N HCl in leak‑proof container; write total volume on container and requisition; avoid direct sunlight; avoid antihistamines, oral corticosteroids, H2 blockers for 24 h prior.
Patient Preparation
Avoid direct sunlight; refrain from antihistamines, oral corticosteroids, and H2 blockers for 24 h prior to collection.
Storage Instructions
Transport refrigerated with cold packs.
Causes for Rejection
Random (untimed) urine
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 14 days |
| Frozen | 14 days |