Lactate/Pyruvate, Filtrate
Use
This test measures lactic acid, pyruvic acid, and the lactate/pyruvate ratio in a protein‑free filtrate of whole blood, providing critical insight into metabolic and mitochondrial disorders. An elevated lactate-to-pyruvate (L:P) ratio may indicate possible inborn errors of metabolism or impaired cellular respiration, especially in the context of lactic acidosis.
Special Instructions
Not provided.
Limitations
This test has not been cleared or approved by the FDA; validation was performed under CLIA regulations. Analytical performance characteristics have been determined by Quest Diagnostics but are not FDA‑approved.
Methodology
Other
Biomarkers
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
4 mL
Minimum Volume
1 mL
Container
sodium fluoride (gray‑top) tube
Collection Instructions
Drawn from fasting patient without use of tourniquet and immediately mixed with 4 mL ice‑cold 7% (w/v) Perchloric Acid. Let mixture stand for 10 minutes and centrifuge. Submit supernatant fluid for assay.
Patient Preparation
Fasting sample required
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 3 hours |
| Refrigerated | 48 hours |
| Frozen | 30 days |
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