Parietal Cell Antibody, ELISA
Also known as: Gastric Parietal Cell Antibody, PCA, GPA, Gastric Parietal Antibody
Use
Gastric parietal cell antibodies are commonly found in patients with pernicious anemia and autoimmune chronic atrophic gastritis. The antigen targeted by these antibodies is the H+/K+ ATPase gastric proton pump responsible for acid production in the stomach. Detection of these antibodies supports the evaluation of autoimmune gastric disorders and pernicious anemia.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (ELISA)
Biomarkers
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red top tube (no additive); Serum Separator Tube (SST)
Collection Instructions
Collect serum after clotting; allow 1‑2 mL blood to clot, then separate serum
Causes for Rejection
Gross hemolysis; Lipemia; Microbially contaminated serum; heavy visible particulate
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 14 days |
| Frozen | 30 days |