Casandra
Casandra Test Code QD29961Version 1 (DRAFT)
Performing Lab
PD‑L1, IHC with Interpretation
Also known as: PDL1, VENTANA® PD-L1 (SP142) Assay, SP142 (Ventana)
Clinical Use
Order TestUse
This PD‑L1 qualitative assay is intended for use in the detection of PD‑L1 expression in cancers, particularly in solid tumors. Measurement of PD‑L1 expression can inform the potential use of immunotherapies targeting the PD‑1/PD‑L1 pathway, which have demonstrated durable anti‑tumor effects in a subset of patients with solid tumors.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Immunoassay (IHC)
Biomarkers
PD‑L1
ProteinIHC • Expression • Ordinal Score (e.g., TPS, CPS, H-score)
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Formalin‑fixed, paraffin‑embedded tissue block
Storage Instructions
Room temperature for tissue block; Refrigerated (cold packs) for slides
Causes for Rejection
Previously stained slides; Cytospins; Monolayer preparation/slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 years for tissue block; 30 days for slides |
| Refrigerated | 5 years for tissue block; 30 days for slides |
| Frozen | Unacceptable |