Use

The assay is intended for the detection of IgG and IgM class antibodies to the phosphatidylserine/prothrombin complex in serum or plasma. A positive result suggests the possibility of autoimmune thrombotic disorders such as antiphospholipid syndrome (APS) or lupus-like thrombotic diseases. PS–PT IgG and IgM antibodies are non-criteria APS antibodies and may support APS diagnosis when other standard antibodies (eg, cardiolipin, β2‑glycoprotein I, lupus anticoagulant) are negative. They also correlate with lupus anticoagulant presence and may serve as a surrogate when anticoagulants interfere with lupus anticoagulant testing.