Protein C, Antigen
Also known as: PC Antigen, Antigen, Protein C, Protein C
Use
Protein C antigen measurement is performed to help confirm and characterize Protein C deficiency, which may increase risk of abnormal blood clotting. It may be used following Protein C activity testing when activity is below threshold levels, and can assist in the diagnosis of congenital or acquired deficiencies affecting coagulation.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (ELISA)
Biomarkers
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.5 mL
Container
3.2% sodium citrate (light blue-top) tube
Collection Instructions
Draw blood in light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3–4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using plastic pipette, remove plasma, avoid WBC/platelet buffy layer into plastic vial(s). Centrifuge second time and transfer platelet‑poor plasma into new plastic vial(s). Freeze immediately and transport on dry ice.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 14 days |