Prothrombin (Factor II) 20210G>A Mutation Analysis
Use
The Prothrombin (Factor II) 20210G>A mutation (G20210A) is one of the most common inherited risk factors for venous thrombosis, present in approximately 2.3% of the general population, compared with higher frequencies in patients with venous thrombosis (around 6%) and familial thrombosis (approximately 18%). Identification of this mutation aids in thrombotic risk assessment and clinical management. ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/Medfusion/test/681363?utm_source=openai))
Special Instructions
Not provided.
Limitations
This test was developed and its analytical performance characteristics were determined by Quest Diagnostics. It has not been cleared or approved by the FDA, but has been validated under CLIA regulations for clinical use. ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/Medfusion/test/681363?utm_source=openai))
Methodology
PCR-based (PCR)
Biomarkers
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
3 mL
Container
EDTA (lavender-top) tube; alternative: EDTA (royal blue-top), sodium heparin (green-top), lithium heparin (green-top), ACD solution A/B (yellow-top)
Collection Instructions
Whole blood collected in an EDTA (lavender‑top) tube is preferred; alternative anticoagulants acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 days |
| Refrigerated | 8 days |
| Frozen | 30 days |