QNatal® Advanced
Also known as: NIPT
Use
QNatal® Advanced is a noninvasive cell‑free DNA (cfDNA) prenatal screening test performed on maternal blood, designed to assess risk for common fetal chromosomal aneuploidies—including trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome), sex chromosome abnormalities (e.g., monosomy X, XXY, XXX, XYY), and, if elected, selected microdeletion syndromes (1p36, 4p, 5p, 8q, 11q, 15q, 22q) and fetal sex. It is intended as a screening tool—not diagnostic—and positive or increased‑risk results should be followed by genetic counseling and diagnostic testing when clinically indicated. It should not be used prior to 10 weeks gestation.
Special Instructions
Not provided.
Limitations
QNatal® Advanced is a screening—not diagnostic—test and cannot detect copy number abnormalities outside its target chromosomes or regions or nonsyndromic congenital anomalies such as neural tube defects or ventral wall defects. Results may be affected by low fetal fraction; false positives and negatives may occur due to factors such as confined placental mosaicism, vanishing twin, fetal or maternal mosaicism, fibroids, or maternal malignancy.
Methodology
NGS (Targeted)
Biomarkers
LOINC Codes
- 33882-2 - Collect Date
Result Turnaround Time
7 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Other tests from different labs that may be relevant